Primary central nervous system lymphoma in an immunocompetent host.

Dr. Felipe Slaviero – Edifício das Clínicas Rua Teixeira Soares 885 / 10o andar 99010-901 Passo Fundo RS Brasil. E-mail: [email protected] Primary central nervous system lymphoma (PCNSL) is a form of extranodal non-Hodgkin’s lymphoma, which occurs in the brain, leptomeninges, spinal cord, or eyes. PCNSL is an uncommon intracranial neoplasm, particularly in the immunocompetent patient population. An immunosuppressive state is the unique established risk factor for PCNSL, and the HIV-related primary lymphoma is 3600-fold more common compared with the general population. This tumor constitutes 0.3–1.5% of all intracranial neoplasm in patients without AIDS. The age-adjusted incidence in the United States has augmented 3 folds in the last three decades, passing from 0.16 per 100000 between 1973–1984 to 0.48 per 100000 between 1985–1997, although current data suggests a plateau or a slightly decrease in the annual incidence. The purpose of this study is to report and discuss the uncommon occurrence of PCNSL in an immunocompetent patient.